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Microbe‐Dependent Exacerbated Alveolar Bone Destruction in Heterozygous Cherubism Mice
Cherubism (OMIM#118400) is a craniofacial disorder characterized by destructive jaw expansion. Gain‐of‐function mutations in SH3‐domain binding protein 2 (SH3BP2) are responsible for this rare disorder. We have previously shown that homozygous knock‐in (KI) mice (Sh3bp2 (KI/KI)) recapitulate human c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285758/ https://www.ncbi.nlm.nih.gov/pubmed/32537546 http://dx.doi.org/10.1002/jbm4.10352 |