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Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β-catenin signaling pathway in colon cancer

The downregulation of farnesoid X receptor (FXR; gene name, nuclear receptor subfamily 1 group h member 4), an enteric nuclear bile acid receptor, has been reported in colorectal carcinoma (CRC), and FXR expression has been inversely correlated with CRC stage and clinical outcome. FXR knockdown in c...

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Detalles Bibliográficos
Autores principales: Mao, Jiayu, Chen, Xueqi, Wang, Chunsaier, Li, Wenbin, Li, Jingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285806/
https://www.ncbi.nlm.nih.gov/pubmed/32565960
http://dx.doi.org/10.3892/ol.2020.11545