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TGF-β1 induces N-cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells

Squamous cell carcinoma (SCC) is the most frequent cancer that develops in the oral cavity. Epithelial-mesenchymal transition (EMT) is known to play an important role in the process of metastasis of SCC cells. In our previous study, we demonstrated that TGF-β1 induced EMT in the human oral SCC (hOSC...

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Detalles Bibliográficos
Autores principales: Hirano, Taifu, Saito, Daishi, Yamada, Hiroyuki, Ishisaki, Akira, Kamo, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285821/
https://www.ncbi.nlm.nih.gov/pubmed/32565972
http://dx.doi.org/10.3892/ol.2020.11582