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Chloroquine increases the anti-cancer activity of epirubicin in A549 lung cancer cells

The present study investigated whether the autophagy inhibitor chloroquine (CQ) can improve the sensitivity of the A549 lung cancer cell line to epirubicin (EPI). The Cell Counting Kit 8 (CCK8) assay was used to determine the EPI IC(50) in A549 cells treated for 72 h. A549 cells were treated with We...

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Detalles Bibliográficos
Autores principales: Liang, Ai-Ling, Zhang, Jing, Du, Shen-Lin, Zhang, Bin, Ma, Xuan, Wu, Cui-Yun, Liu, Yong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285842/
https://www.ncbi.nlm.nih.gov/pubmed/32565933
http://dx.doi.org/10.3892/ol.2020.11567