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P4HB modulates epithelial-mesenchymal transition and the β-catenin/Snail pathway influencing chemoresistance in liver cancer cells

The aim of the present study was to investigate the role of prolyl 4-hydroxylase beta polypeptide (P4HB) in the chemoresistance of liver cancer. Drug-resistant liver cancer cell lines, such as HepG2/adriamycin (ADR) cells, were treated and screened using adriamycin. Gene interference was used to sil...

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Detalles Bibliográficos
Autores principales: Ma, Xing, Wang, Jiening, Zhuang, Juhua, Ma, Xiaokun, Zheng, Ni, Song, Yanan, Xia, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285890/
https://www.ncbi.nlm.nih.gov/pubmed/32565952
http://dx.doi.org/10.3892/ol.2020.11569