Cargando…
P4HB modulates epithelial-mesenchymal transition and the β-catenin/Snail pathway influencing chemoresistance in liver cancer cells
The aim of the present study was to investigate the role of prolyl 4-hydroxylase beta polypeptide (P4HB) in the chemoresistance of liver cancer. Drug-resistant liver cancer cell lines, such as HepG2/adriamycin (ADR) cells, were treated and screened using adriamycin. Gene interference was used to sil...
Autores principales: | Ma, Xing, Wang, Jiening, Zhuang, Juhua, Ma, Xiaokun, Zheng, Ni, Song, Yanan, Xia, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285890/ https://www.ncbi.nlm.nih.gov/pubmed/32565952 http://dx.doi.org/10.3892/ol.2020.11569 |
Ejemplares similares
-
P4HB promotes HCC tumorigenesis through downregulation of GRP78 and subsequent upregulation of epithelial-to-mesenchymal transition
por: Xia, Wei, et al.
Publicado: (2016) -
MiR-363 inhibits cisplatin chemoresistance of epithelial ovarian cancer by regulating snail-induced epithelial-mesenchymal transition
por: Cao, Lanqin, et al.
Publicado: (2018) -
Nestin overexpression in hepatocellular carcinoma associates with epithelial-mesenchymal transition and chemoresistance
por: Zhang, Yan, et al.
Publicado: (2016) -
PYCR1 interference inhibits cell growth and survival via c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathway in hepatocellular cancer
por: Zhuang, Juhua, et al.
Publicado: (2019) -
CDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression
por: Yu, Junhui, et al.
Publicado: (2020)