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Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel

Peptidic toxins that target specifically mammalian channels and receptors can be found in the venom of animals. These toxins are rarely used directly as tools for biochemical experiments, and need to be modified via the attachment of chemical groups (e.g., radioactive or fluorescent moieties). Ideal...

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Detalles Bibliográficos
Autores principales: Vasseur, Lucie, Chavanieu, Alain, Combemale, Stéphanie, Caumes, Cécile, Béroud, Rémy, De Waard, Michel, Ducrot, Pierre, Boutin, Jean A., Ferry, Gilles, Cens, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285999/
https://www.ncbi.nlm.nih.gov/pubmed/32550567
http://dx.doi.org/10.1016/j.toxcx.2019.100010