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The use of the dynamic weight bearing test to assess the effects of acute, intramuscularly administered botulinum neurotoxin type A1 in rats

Assessing the efficacy of botulinum neurotoxin (BoNT) in vivo is essential given the growing number of BoNT products used in the clinic. Here, we evaluated the dynamic weight bearing (DWB) test for sensitivity to paralytic effects of BoNT-A following intramuscular administration. The toxin was admin...

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Detalles Bibliográficos
Autores principales: Cornet, Sylvie, Périer, Cindy, Wagner, Stéphanie, Andriambeloson, Emile, Pouzet, Bruno, Kalinichev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286111/
https://www.ncbi.nlm.nih.gov/pubmed/32550595
http://dx.doi.org/10.1016/j.toxcx.2020.100041