N -Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation

The release of calcium ions (Ca (2+) ) from the endoplasmic reticulum (ER) and related store-operated calcium entry (SOCE) regulate maturation of normal megakaryocytes. The N -methyl-D-aspartate (NMDA) receptor (NMDAR) provides an additional mechanism for Ca (2+) influx in megakaryocytic cells, but...

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Detalles Bibliográficos
Autores principales: Hearn, James I., Green, Taryn N., Chopra, Martin, Nursalim, Yohanes N. S., Ladvanszky, Leandro, Knowlton, Nicholas, Blenkiron, Cherie, Poulsen, Raewyn C., Singleton, Dean C., Bohlander, Stefan K., Kalev-Zylinska, Maggie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286128/
https://www.ncbi.nlm.nih.gov/pubmed/32289863
http://dx.doi.org/10.1055/s-0040-1708483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286128/
https://www.ncbi.nlm.nih.gov/pubmed/32289863
http://dx.doi.org/10.1055/s-0040-1708483

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