Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes

3D cell cultures enable the in vitro study of dynamic biological processes such as the cell cycle, but their use in high-throughput screens remains impractical with conventional fluorescent microscopy. Here, we present a screening workflow for the automated evaluation of mitotic phenotypes in 3D cel...

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Detalles Bibliográficos
Autores principales: Eismann, Björn, Krieger, Teresa G., Beneke, Jürgen, Bulkescher, Ruben, Adam, Lukas, Erfle, Holger, Herrmann, Carl, Eils, Roland, Conrad, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Tools and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286290/
https://www.ncbi.nlm.nih.gov/pubmed/32295847
http://dx.doi.org/10.1242/jcs.245043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286290/
https://www.ncbi.nlm.nih.gov/pubmed/32295847
http://dx.doi.org/10.1242/jcs.245043

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