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Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes
3D cell cultures enable the in vitro study of dynamic biological processes such as the cell cycle, but their use in high-throughput screens remains impractical with conventional fluorescent microscopy. Here, we present a screening workflow for the automated evaluation of mitotic phenotypes in 3D cel...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286290/ https://www.ncbi.nlm.nih.gov/pubmed/32295847 http://dx.doi.org/10.1242/jcs.245043 |