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Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type‐1 domain‐containing 7A in glioblastoma

BACKGROUND: Aquaporin (AQP) 1 expression has been linked with tumor malignancy but its role in glioblastoma (GBM), a lethal glioma, remains to be clarified. METHODS: AQP1 expression was examined in 33 human GBM specimens by immunohistochemistry. GBM cells (U251 and U87) that stably express AQP1 were...

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Detalles Bibliográficos
Autores principales: Oishi, Masahiro, Munesue, Seiichi, Harashima, Ai, Nakada, Mitsutoshi, Yamamoto, Yasuhiko, Hayashi, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286445/
https://www.ncbi.nlm.nih.gov/pubmed/32253832
http://dx.doi.org/10.1002/cam4.3032