Cargando…

Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells

Alternative lengthening of telomeres (ALT) in human cells is a conserved process that is often activated in telomerase-deficient human cancers. This process exploits components of the recombination machinery to extend telomere ends, thus allowing for increased proliferative potential. Human MUS81 (M...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwartz, Erin K., Hung, Shih-Hsun, Meyer, Damon, Piazza, Aurèle, Yan, Kevin, Fu, Becky Xu Hua, Heyer, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286520/
https://www.ncbi.nlm.nih.gov/pubmed/32469862
http://dx.doi.org/10.1371/journal.pgen.1008816