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Global changes in nitration levels and DNA binding profile of Trypanosoma cruzi histones induced by incubation with host extracellular matrix

Adhesion of T. cruzi trypomastigotes to components of the extracellular matrix (ECM) is an important step in mammalian host cell invasion. We have recently described a significant increase in the tyrosine nitration levels of histones H2A and H4 when trypomastigotes are incubated with components of t...

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Detalles Bibliográficos
Autores principales: Magalhães, Rubens Daniel Miserani, Mattos, Eliciane Cevolani, Rozanski, Andrei, Galante, Pedro Alexandre Favoretto, Palmisano, Giuseppe, Cruz, Angela Kaysel, Colli, Walter, Camargo, Anamaria Aranha, Alves, Maria Júlia Manso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286532/
https://www.ncbi.nlm.nih.gov/pubmed/32469928
http://dx.doi.org/10.1371/journal.pntd.0008262