Detecting and predicting neutralization of alemtuzumab responses in MS

OBJECTIVE: To test the hypothesis that antidrug antibodies (ADAs) against alemtuzumab could become relevant after repeated treatments for some individuals, possibly explaining occasional treatment resistance. METHODS: Recombinant alemtuzumab single-chain variable fragment antibody with a dual tandem...

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Detalles Bibliográficos
Autores principales: Saxena, Gauri, Moore, James M., Jones, Meleri, Pryce, Gareth, Ali, Liaqat, Leisegang, Georgia R., Vijay, Vivek, Loveless, Samantha, Robertson, Neil P., Schmierer, Klaus, Giovannoni, Gavin, Gnananpavan, Sharmilee, Baker, David, Tallantyre, Emma C., Kang, Angray S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286660/
https://www.ncbi.nlm.nih.gov/pubmed/32499328
http://dx.doi.org/10.1212/NXI.0000000000000767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286660/
https://www.ncbi.nlm.nih.gov/pubmed/32499328
http://dx.doi.org/10.1212/NXI.0000000000000767

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