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Accelerated evolution of a minimal 63–amino acid dual transcription factor
Transcription factors control gene expression in all life. This raises the question of what is the smallest protein that can support such activity. In nature, Cro from bacteriophage λ is one of the smallest known repressors (66 amino acids), and activators are typically much larger (e.g., λ cI, 237...
Autores principales: | Brödel, Andreas K., Rodrigues, Rui, Jaramillo, Alfonso, Isalan, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286687/ https://www.ncbi.nlm.nih.gov/pubmed/32577520 http://dx.doi.org/10.1126/sciadv.aba2728 |
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