Multi-region exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components

Immature teratoma is a subtype of malignant germ cell tumor of the ovary that occurs most commonly in the first three decades of life, frequently with bilateral ovarian disease. Despite being the second most common malignant germ cell tumor of the ovary, little is known about its genetic underpinnin...

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Detalles Bibliográficos
Autores principales: Heskett, Michael B., Sanborn, John Z., Boniface, Christopher, Goode, Benjamin, Chapman, Jocelyn, Garg, Karuna, Rabban, Joseph T., Zaloudek, Charles, Benz, Stephen C., Spellman, Paul T., Solomon, David A., Cho, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286805/
https://www.ncbi.nlm.nih.gov/pubmed/31911616
http://dx.doi.org/10.1038/s41379-019-0446-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286805/
https://www.ncbi.nlm.nih.gov/pubmed/31911616
http://dx.doi.org/10.1038/s41379-019-0446-y

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