Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

Nuclear protein of the testis (NUT) midline carcinoma (NMC), is a rare and highly aggressive form of undifferentiated squamous cell carcinoma. NMC is molecularly characterized by chromosomal rearrangement of the NUT gene to another gene, most commonly the bromodomain and extraterminal domain (BET) g...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Zegar, Tim, Lucas, Anais, Morrison-Smith, Chevaun, Knox, Tatiana, French, Christopher A., Knapp, Stefan, Müller, Susanne, Siveke, Jens T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286816/
https://www.ncbi.nlm.nih.gov/pubmed/32366905
http://dx.doi.org/10.1038/s41388-020-1301-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286816/
https://www.ncbi.nlm.nih.gov/pubmed/32366905
http://dx.doi.org/10.1038/s41388-020-1301-9

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