Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells

Methotrexate (MTX) is an efficient chemotherapeutic and immunosuppressant drug, but the hepatotoxicity of MTX limits its clinical use. Naringin (Nar) is a flavonoid derived from Citrus paradise, and has been shown to possess several pharmacological activities, including free-radical scavenging and a...

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Detalles Bibliográficos
Autores principales: Elsawy, Hany, Algefare, Abdulmohsen I., Alfwuaires, Manal, Khalil, Mahmoud, Elmenshawy, Omar M., Sedky, Azza, Abdel-Moneim, Ashraf M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Therapeutics & Molecular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286878/
https://www.ncbi.nlm.nih.gov/pubmed/32458964
http://dx.doi.org/10.1042/BSR20193686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286878/
https://www.ncbi.nlm.nih.gov/pubmed/32458964
http://dx.doi.org/10.1042/BSR20193686

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