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Transcriptomic study in women with trisomy 21 identifies a possible role of the GTPases of the immunity-associated proteins (GIMAP) in the protection of breast cancer

Background: People with trisomy 21 (T21) are predisposed to developing hematological tumors, but have significantly lower-than-expected age-adjusted incidence rates of having a solid tumor. Material and methods: To identify novel genetic factors implicated in the lower breast cancer (BC) frequency o...

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Detalles Bibliográficos
Autores principales: Mégarbané, André, Piquemal, David, Rebillat, Anne-Sophie, Stora, Samantha, Pierrat, Fabien, Bruno, Roman, Noguier, Florian, Mircher, Clotilde, Ravel, Aimé, Vilaire-Meunier, Marie, Durand, Sophie, Lefranc, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286899/
https://www.ncbi.nlm.nih.gov/pubmed/32523132
http://dx.doi.org/10.1038/s41598-020-66469-w