Distinct metabolic states of a cell guide alternate fates of mutational buffering through altered proteostasis

Metabolic changes alter the cellular milieu; can this also change intracellular protein folding? Since proteostasis can modulate mutational buffering, if change in metabolism has the ability to change protein folding, arguably, it should also alter mutational buffering. Here we find that altered cel...

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Detalles Bibliográficos
Autores principales: Verma, Kanika, Saxena, Kanika, Donaka, Rajashekar, Chaphalkar, Aseem, Rai, Manish Kumar, Shukla, Anurag, Zaidi, Zainab, Dandage, Rohan, Shanmugam, Dhanasekaran, Chakraborty, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286901/
https://www.ncbi.nlm.nih.gov/pubmed/32522991
http://dx.doi.org/10.1038/s41467-020-16804-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286901/
https://www.ncbi.nlm.nih.gov/pubmed/32522991
http://dx.doi.org/10.1038/s41467-020-16804-6

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