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SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response

SHQ1 was reported to control the biogenesis and assembly of H/ACA ribonucleoprotein particles (RNPs). It was independently isolated as a growth suppressor, GRIM1, in a genetic screen. Recent studies have indicated that SHQ1 inhibits prostate cancer growth and metastasis. SHQ1 facilitates MYC RNA spl...

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Detalles Bibliográficos
Autores principales: Liu, Huimin, Xie, Siqi, Fang, Fang, Kalvakolanu, Dhananjaya V., Xiao, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286909/
https://www.ncbi.nlm.nih.gov/pubmed/32522979
http://dx.doi.org/10.1038/s41419-020-2656-0