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Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls

Amyotrophic lateral sclerosis (ALS) is a disorder with immune alterations that augment disease severity. M2 macrophages benefit diabetic and nephrotic mice by suppressing the pro-inflammatory state. However, neither have M2 cells been investigated in ALS nor have human induced pluripotent stem cell...

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Detalles Bibliográficos
Autores principales: Zhao, Weihua, Beers, David R., Thonhoff, Jason R., Thome, Aaron D., Faridar, Alireza, Wang, Jinghong, Wen, Shixiang, Ornelas, Loren, Sareen, Dhruv, Goodridge, Helen S., Svendsen, Clive N., Appel, Stanley H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286967/
https://www.ncbi.nlm.nih.gov/pubmed/32521508
http://dx.doi.org/10.1016/j.isci.2020.101192