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TDP-43 Is Elevated in Plasma Neuronal-Derived Exosomes of Patients With Alzheimer’s Disease

BACKGROUND: Recently, TDP-43 has been recognized as a common proteinopathy in the “oldest old” and a neuropathological comorbidity in patients with Alzheimer’s disease (AD). However, since it has a low concentration in cerebrospinal fluid, the presence of TDP-43 in AD is rarely investigated in vivo....

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Gu, Dongmei, Meng, Meng, Gordon, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287025/
https://www.ncbi.nlm.nih.gov/pubmed/32581773
http://dx.doi.org/10.3389/fnagi.2020.00166