In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation

The tumor immune microenvironment (TIME) of head and neck squamous cell carcinomas (HNSCC) and other solid malignancies is a key determinant of therapy response and prognosis. Among other factors, it is shaped by the tumor mutational burden and defects in DNA repair enzymes. Based on the TCGA databa...

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Detalles Bibliográficos
Autores principales: Krupar, Rosemarie, Watermann, Christian, Idel, Christian, Ribbat-Idel, Julika, Offermann, Anne, Pasternack, Helen, Kirfel, Jutta, Sikora, Andrew G., Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287052/
https://www.ncbi.nlm.nih.gov/pubmed/32523042
http://dx.doi.org/10.1038/s41598-020-66329-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287052/
https://www.ncbi.nlm.nih.gov/pubmed/32523042
http://dx.doi.org/10.1038/s41598-020-66329-7

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