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The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization

Cisplatin is one of the most potent chemotherapy drugs to treat cancers, but its clinical application remains limited due to severe nephrotoxicity. Several approaches have been developed to minimize such side effects, notably including chronotherapy, a well-known strategy based on the circadian cloc...

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Detalles Bibliográficos
Autores principales: Zha, Min, Tian, Ting, Xu, Weilong, Liu, Su, Jia, Jia, Wang, Lijuan, Yan, Qianhua, Li, Nan, Yu, Jiangyi, Huang, Liji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287064/
https://www.ncbi.nlm.nih.gov/pubmed/32522976
http://dx.doi.org/10.1038/s41419-020-2655-1