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The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization
Cisplatin is one of the most potent chemotherapy drugs to treat cancers, but its clinical application remains limited due to severe nephrotoxicity. Several approaches have been developed to minimize such side effects, notably including chronotherapy, a well-known strategy based on the circadian cloc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287064/ https://www.ncbi.nlm.nih.gov/pubmed/32522976 http://dx.doi.org/10.1038/s41419-020-2655-1 |