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Tumor-associated macrophages in classical Hodgkin lymphoma: hormetic relationship to outcome

Commonly attributed to the prevalence of M2 macrophages, tumor-associated macrophages (TAM) are linked to poor outcome in Hodgkin lymphoma (HL). MYC is supposed to control the expression of M2-specific genes in macrophages, and deficiency in MYC-positive macrophages inhibits tumor growth in mouse mo...

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Detalles Bibliográficos
Autores principales: Werner, Laura, Dreyer, Johannes H., Hartmann, David, Barros, Mário Henrique M., Büttner-Herold, Maike, Grittner, Ulrike, Niedobitek, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287068/
https://www.ncbi.nlm.nih.gov/pubmed/32523087
http://dx.doi.org/10.1038/s41598-020-66010-z