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Distinct pre-initiation steps in human mitochondrial translation

Translation initiation in human mitochondria relies upon specialized mitoribosomes and initiation factors, mtIF2 and mtIF3, which have diverged from their bacterial counterparts. Here we report two distinct mitochondrial pre-initiation assembly steps involving those factors. Single-particle cryo-EM...

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Detalles Bibliográficos
Autores principales: Khawaja, Anas, Itoh, Yuzuru, Remes, Cristina, Spåhr, Henrik, Yukhnovets, Olessya, Höfig, Henning, Amunts, Alexey, Rorbach, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287080/
https://www.ncbi.nlm.nih.gov/pubmed/32522994
http://dx.doi.org/10.1038/s41467-020-16503-2