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Distinct pre-initiation steps in human mitochondrial translation
Translation initiation in human mitochondria relies upon specialized mitoribosomes and initiation factors, mtIF2 and mtIF3, which have diverged from their bacterial counterparts. Here we report two distinct mitochondrial pre-initiation assembly steps involving those factors. Single-particle cryo-EM...
Autores principales: | Khawaja, Anas, Itoh, Yuzuru, Remes, Cristina, Spåhr, Henrik, Yukhnovets, Olessya, Höfig, Henning, Amunts, Alexey, Rorbach, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287080/ https://www.ncbi.nlm.nih.gov/pubmed/32522994 http://dx.doi.org/10.1038/s41467-020-16503-2 |
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