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Activation of GPR35 protects against cerebral ischemia by recruiting monocyte-derived macrophages

Pamoic acid is a potent ligand for G protein Coupled Receptor 35 (GPR35) and exhibits antinociceptive property. GPR35 activation leads to increased energy utilization and the expression of anti-inflammatory genes. However, its role in brain disorders, especially in stroke, remains unexplored. Here w...

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Detalles Bibliográficos
Autores principales: Sharmin, Ozayra, Abir, Ariful Haque, Potol, Abdullah, Alam, Mahabub, Banik, Jewel, Rahman, A.F.M. Towheedur, Tarannum, Nuzhat, Wadud, Rasiqh, Habib, Zaki Farhad, Rahman, Mahbubur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287103/
https://www.ncbi.nlm.nih.gov/pubmed/32523084
http://dx.doi.org/10.1038/s41598-020-66417-8