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Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy

The massive production and activation of myofibroblasts (MFB) is key to the development of liver fibrosis. In many studies, it has been proven that hepatocytes are an important part of MFB, and can be transformed into MFB through epithelial-mesenchymal transition (EMT) during hepatic fibrogenesis. I...

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Detalles Bibliográficos
Autores principales: Kong, Desong, Zhang, Zili, Chen, Liping, Huang, Weifang, Zhang, Feng, Wang, Ling, Wang, Yu, Cao, Peng, Zheng, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287144/
https://www.ncbi.nlm.nih.gov/pubmed/32526690
http://dx.doi.org/10.1016/j.redox.2020.101600