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Differential Cytotoxic Function of Resident and Non-resident CD8+ T Cells in the Human Female Reproductive Tract Before and After Menopause

The functional characterization and regulation of tissue resident and non-resident CD8+ T cells in the human female reproductive tract (FRT) as women age remains a gap in our knowledge. Here we characterized the cytotoxic activity and granular contents of CD8+ T cells from the FRT in pre- and postme...

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Detalles Bibliográficos
Autores principales: Rodriguez-Garcia, Marta, Shen, Zheng, Fortier, Jared M., Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287154/
https://www.ncbi.nlm.nih.gov/pubmed/32582183
http://dx.doi.org/10.3389/fimmu.2020.01096