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Comparison of AAV-Mediated Optogenetic Vision Restoration between Retinal Ganglion Cell Expression and ON Bipolar Cell Targeting

The loss of photoreceptors in individuals with retinal degenerative diseases leads to partial or complete blindness. Optogenetic therapy is a promising approach for restoring vision to the blind. Multiple strategies have been employed by targeting genetically encoded light sensors, particularly chan...

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Detalles Bibliográficos
Autores principales: Lu, Qi, Ganjawala, Tushar H., Krstevski, Andrea, Abrams, Gary W., Pan, Zhuo-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287188/
https://www.ncbi.nlm.nih.gov/pubmed/32548211
http://dx.doi.org/10.1016/j.omtm.2020.05.009