Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy

OBJECTIVE: Bleomycin is an important chemotherapeutic drug that activates premature senescence to decrease the tumorigenic process. We aimed to investigate the role of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in bleomycin-induced premature senescence in lung cancer cells. METH...

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Detalles Bibliográficos
Autores principales: Sai, Xiaoyan, Qin, Chu, Wu, Yan, Zhao, Yinying, Bian, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Validation Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287201/
https://www.ncbi.nlm.nih.gov/pubmed/32436415
http://dx.doi.org/10.1177/0300060520923522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287201/
https://www.ncbi.nlm.nih.gov/pubmed/32436415
http://dx.doi.org/10.1177/0300060520923522

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