Cargando…
Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy
OBJECTIVE: Bleomycin is an important chemotherapeutic drug that activates premature senescence to decrease the tumorigenic process. We aimed to investigate the role of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in bleomycin-induced premature senescence in lung cancer cells. METH...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287201/ https://www.ncbi.nlm.nih.gov/pubmed/32436415 http://dx.doi.org/10.1177/0300060520923522 |