Cargando…

Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes

The IKs channel complex is formed by the co-assembly of Kv7.1 (KCNQ1), a voltage-gated potassium channel, with its β-subunit, KCNE1 and the association of numerous accessory regulatory molecules such as PIP2, calmodulin, and yotiao. As a result, the IKs potassium current shows kinetic and regulatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yundi, Eldstrom, Jodene, Fedida, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287213/
https://www.ncbi.nlm.nih.gov/pubmed/32581825
http://dx.doi.org/10.3389/fphys.2020.00504