Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments

Mathematical models of ion channels, which constitute indispensable components of action potential models, are commonly constructed by fitting to whole-cell patch-clamp data. In a previous study, we fitted cell-specific models to hERG1a (Kv11.1) recordings simultaneously measured using an automated...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Chon Lok, Clerx, Michael, Whittaker, Dominic G., Gavaghan, David J., de Boer, Teun P., Mirams, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287334/
https://www.ncbi.nlm.nih.gov/pubmed/32448060
http://dx.doi.org/10.1098/rsta.2019.0348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287334/
https://www.ncbi.nlm.nih.gov/pubmed/32448060
http://dx.doi.org/10.1098/rsta.2019.0348

Ejemplares similares