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Reducing complexity and unidentifiability when modelling human atrial cells

Mathematical models of a cellular action potential (AP) in cardiac modelling have become increasingly complex, particularly in gating kinetics, which control the opening and closing of individual ion channel currents. As cardiac models advance towards use in personalized medicine to inform clinical...

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Detalles Bibliográficos
Autores principales: Houston, C., Marchand, B., Engelbert, L., Cantwell, C. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287336/
https://www.ncbi.nlm.nih.gov/pubmed/32448063
http://dx.doi.org/10.1098/rsta.2019.0339