MICAgen Mice Recapitulate the Highly Restricted but Activation-Inducible Expression of the Paradigmatic Human NKG2D Ligand MICA

NKG2D is a potent activating immunoreceptor expressed on nearly all cytotoxic lymphocytes promoting their cytotoxicity against self-cells expressing NKG2D ligands (NKG2DLs). NKG2DLs are MHC class I-like glycoproteins that usually are not expressed on “healthy” cells. Rather, their surface expression...

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Detalles Bibliográficos
Autores principales: Kim, Younghoon, Born, Christina, Bléry, Mathieu, Steinle, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287395/
https://www.ncbi.nlm.nih.gov/pubmed/32582150
http://dx.doi.org/10.3389/fimmu.2020.00960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287395/
https://www.ncbi.nlm.nih.gov/pubmed/32582150
http://dx.doi.org/10.3389/fimmu.2020.00960

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