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Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives—Biological Activity towards Cancer Cells

In the search for new antitumor agents, aminophosphonic acids and their derivatives based on octahydroquinoxalin-2(1H)-one scaffold were obtained and their cytotoxic properties and a mechanism of action were evaluated. Phosphonic acid and phosphonate moieties increased the antiproliferative activity...

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Detalles Bibliográficos
Autores principales: Iwanejko, Jakub, Wojaczyńska, Elżbieta, Turlej, Eliza, Maciejewska, Magdalena, Wietrzyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287629/
https://www.ncbi.nlm.nih.gov/pubmed/32455965
http://dx.doi.org/10.3390/ma13102393