Cargando…

Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice

Semi-synthetic triterpenoids, bearing cyano enone functionality in ring A, are considered to be novel promising therapeutic agents with complex inhibitory effects on tissue damage, inflammation and tumor growth. Previously, we showed that the cyano enone-containing 18βH-glycyrrhetinic acid derivativ...

Descripción completa

Detalles Bibliográficos
Autores principales: Markov, Andrey V., Sen’kova, Aleksandra V., Salomatina, Oksana V., Logashenko, Evgeniya B., Korchagina, Dina V., Salakhutdinov, Nariman F., Zenkova, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287650/
https://www.ncbi.nlm.nih.gov/pubmed/32455822
http://dx.doi.org/10.3390/molecules25102406