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Streptavidin-Hosted Organocatalytic Aldol Addition

In this report, the streptavidin-biotin technology was applied to enable organocatalytic aldol addition. By attaching pyrrolidine to the valeric motif of biotin and introducing it to streptavidin (Sav), a protein-based organocatalytic system was created, and the aldol addition of acetone with p-nitr...

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Detalles Bibliográficos
Autores principales: Santi, Nicolò, Morrill, Louis C., Luk, Louis Y. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287710/
https://www.ncbi.nlm.nih.gov/pubmed/32466220
http://dx.doi.org/10.3390/molecules25102457