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Streptavidin-Hosted Organocatalytic Aldol Addition
In this report, the streptavidin-biotin technology was applied to enable organocatalytic aldol addition. By attaching pyrrolidine to the valeric motif of biotin and introducing it to streptavidin (Sav), a protein-based organocatalytic system was created, and the aldol addition of acetone with p-nitr...
Autores principales: | Santi, Nicolò, Morrill, Louis C., Luk, Louis Y. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287710/ https://www.ncbi.nlm.nih.gov/pubmed/32466220 http://dx.doi.org/10.3390/molecules25102457 |
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