Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs against Human Coronavirus 229E (HCoV-229E)

Remdesivir is a nucleotide prodrug that is currently undergoing extensive clinical trials for the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and interferes with the action of RNA-dependent RNA polymerase of SARS-COV-2. Herein, we report the antiviral activity o...

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Detalles Bibliográficos
Autores principales: Parang, Keykavous, El-Sayed, Naglaa Salem, Kazeminy, Assad J., Tiwari, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287735/
https://www.ncbi.nlm.nih.gov/pubmed/32429580
http://dx.doi.org/10.3390/molecules25102343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287735/
https://www.ncbi.nlm.nih.gov/pubmed/32429580
http://dx.doi.org/10.3390/molecules25102343

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