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Prevention of 7-Ketocholesterol-Induced Overproduction of Reactive Oxygen Species, Mitochondrial Dysfunction and Cell Death with Major Nutrients (Polyphenols, ω3 and ω9 Unsaturated Fatty Acids) of the Mediterranean Diet on N2a Neuronal Cells

The brain, which is a cholesterol-rich organ, can be subject to oxidative stress in a variety of pathophysiological conditions, age-related diseases and some rare pathologies. This can lead to the formation of 7-ketocholesterol (7KC), a toxic derivative of cholesterol mainly produced by auto-oxidati...

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Detalles Bibliográficos
Autores principales: Yammine, Aline, Nury, Thomas, Vejux, Anne, Latruffe, Norbert, Vervandier-Fasseur, Dominique, Samadi, Mohammad, Greige-Gerges, Hélène, Auezova, Lizette, Lizard, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287847/
https://www.ncbi.nlm.nih.gov/pubmed/32414101
http://dx.doi.org/10.3390/molecules25102296