Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology. In 2017, for the first time we introduced miRNAses–miRNA-targeted conjugates of a catalytic peptide and oligonucleotide...

Descripción completa

Detalles Bibliográficos
Autores principales: Patutina, Olga, Chiglintseva, Daria, Bichenkova, Elena, Gaponova, Svetlana, Mironova, Nadezhda, Vlassov, Valentin, Zenkova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287882/
https://www.ncbi.nlm.nih.gov/pubmed/32466298
http://dx.doi.org/10.3390/molecules25102459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287882/
https://www.ncbi.nlm.nih.gov/pubmed/32466298
http://dx.doi.org/10.3390/molecules25102459

Ejemplares similares