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Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology. In 2017, for the first time we introduced miRNAses–miRNA-targeted conjugates of a catalytic peptide and oligonucleotide...

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Detalles Bibliográficos
Autores principales:	Patutina, Olga, Chiglintseva, Daria, Bichenkova, Elena, Gaponova, Svetlana, Mironova, Nadezhda, Vlassov, Valentin, Zenkova, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287882/ https://www.ncbi.nlm.nih.gov/pubmed/32466298 http://dx.doi.org/10.3390/molecules25102459

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