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Novel Insights into the Thioesterolytic Activity of N-Substituted Pyridinium-4-oximes †
The pyridinium oximes are known esterolytic agents, usually classified in the literature as catalysts, which mimic the catalytic mode of hydrolases. Herein, we combined kinetic and computational studies of the pyridinium-4-oxime-mediated acetylthiocholine (AcSCh(+)) hydrolysis to provide novel insig...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287890/ https://www.ncbi.nlm.nih.gov/pubmed/32455554 http://dx.doi.org/10.3390/molecules25102385 |