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Exploring the Scope of Tandem Palladium and Isothiourea Relay Catalysis for the Synthesis of α-Amino Acid Derivatives

The scope and limitations of a tandem N-allylation/[2,3]-rearrangement protocol are investigated through the incorporation of a variety of functional groups within an allylic phosphate precursor. This method uses readily accessible N,N-dimethylglycine aryl esters and functionalized allylic phosphate...

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Detalles Bibliográficos
Autores principales: Bitai, Jacqueline, Slawin, Alexandra M. Z., Cordes, David B., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287902/
https://www.ncbi.nlm.nih.gov/pubmed/32466341
http://dx.doi.org/10.3390/molecules25102463