Chiral Phase Transfer Catalysis in the Asymmetric Synthesis of a 3,3-Disubstituted Isoindolinone and Determination of Its Absolute Configuration by VCD Spectroscopy

In this work we report our endeavors toward the development of an asymmetric synthesis of a 3,3-disubstituted isoindolinone, dimethyl 2-(1-methyl-3-oxoisoindolin-1-yl)malonate, via asymmetric cascade reaction of 2-acetylbenzonitrile with dimethylmalonate and the determination of its absolute configu...

Descripción completa

Detalles Bibliográficos
Autores principales: Monaco, Guglielmo, Tiffner, Maximilian, Mola, Antonia Di, Herrebout, Wouter, Waser, Mario, Massa, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287911/
https://www.ncbi.nlm.nih.gov/pubmed/32408552
http://dx.doi.org/10.3390/molecules25102272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287911/
https://www.ncbi.nlm.nih.gov/pubmed/32408552
http://dx.doi.org/10.3390/molecules25102272

Ejemplares similares